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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
23.94
Human Site:
S1329
Identified Species:
37.62
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
S1329
E
F
E
K
M
N
Q
S
L
R
L
F
R
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
S1329
E
F
E
K
M
N
Q
S
L
R
L
F
R
E
V
Dog
Lupus familis
XP_531814
1283
145094
S1252
E
F
E
K
M
T
Q
S
L
R
L
F
R
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
S1327
E
F
E
R
M
N
Q
S
L
R
L
F
R
G
V
Rat
Rattus norvegicus
XP_002726765
1361
151628
A1330
E
F
E
R
M
N
Q
A
L
Q
L
F
R
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
S1435
E
F
E
K
K
T
M
S
L
R
I
F
R
F
L
Frog
Xenopus laevis
NP_001089247
1340
149481
S1307
Q
K
A
R
E
F
E
S
L
T
L
S
L
K
L
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
S1338
D
F
E
R
S
T
V
S
L
R
I
F
K
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
I1160
Q
R
K
I
T
A
K
I
V
A
A
T
A
G
N
Honey Bee
Apis mellifera
XP_392346
1120
127429
K1090
S
R
A
H
E
I
S
K
K
L
E
Q
E
T
N
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
L1156
S
N
K
F
A
S
N
L
I
I
D
P
K
I
R
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
V1292
I
P
D
E
I
I
L
V
A
R
Q
K
A
K
H
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
S1255
K
M
A
V
L
I
R
S
L
I
N
A
T
T
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
M1288
T
D
H
K
L
A
A
M
I
K
Q
I
I
S
S
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
L1212
D
G
L
K
N
T
K
L
G
S
G
E
G
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
80
N.A.
N.A.
60
20
40
N.A.
0
0
0
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
100
N.A.
N.A.
73.3
53.3
80
N.A.
26.6
0
26.6
33.3
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
7
14
7
7
7
7
7
7
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
7
7
0
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
40
0
47
7
14
0
7
0
0
0
7
7
7
27
0
% E
% Phe:
0
47
0
7
0
7
0
0
0
0
0
47
0
7
0
% F
% Gly:
0
7
0
0
0
0
0
0
7
0
7
0
7
14
0
% G
% His:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
7
7
20
0
7
14
14
14
7
7
7
0
% I
% Lys:
7
7
14
40
7
0
14
7
7
7
0
7
14
20
0
% K
% Leu:
0
0
7
0
14
0
7
14
60
7
40
0
7
0
27
% L
% Met:
0
7
0
0
34
0
7
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
7
27
7
0
0
0
7
0
0
0
14
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
14
0
0
0
0
0
34
0
0
7
14
7
0
0
0
% Q
% Arg:
0
14
0
27
0
0
7
0
0
47
0
0
40
0
7
% R
% Ser:
14
0
0
0
7
7
7
54
0
7
0
7
0
7
14
% S
% Thr:
7
0
0
0
7
27
0
0
0
7
0
7
7
14
0
% T
% Val:
0
0
0
7
0
0
7
7
7
0
0
0
0
7
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _